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contraindication
nounmeaning in plain English
A time when a medicine or treatment should not be used because it could cause harm.
for example
If someone is pregnant, that is a contraindication for taking that drug.
A contraindication is like a big red warning sign that says, 'Don’t use this!' Why? Because using it could make things worse instead of better. Imagine if someone with a peanut allergy took medicine made with peanuts—it would be a clear contraindication.